Solid, rapidly released medicament preparations containing...

A - Human Necessities – 61 – K

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A61K 31/44 (2006.01) A61K 9/14 (2006.01) A61K 9/16 (2006.01) A61K 9/20 (2006.01) A61K 31/455 (2006.01)

Patent

CA 1184118

BAYER AKTIENGESELLSCHAFT Solid, rapidly released medicament preparations contain- ing dihydropyridines, and processes for their preparation ABSTRACT OF THE DISCLOSURE Solid dihydropyridines, e.g. nifedipine and nimodipine preparations having a maximum standard deviation of the active compound content of 3% contain 1 part by weight of nifedipine, 2 to 6 parts by weight of PVP with a mean molecular weight of 15,000 to 50,000, 3.5 to 15 parts by weight of cellulose, 0.25 to 4 parts by weight of starch and 0.5 to 4 parts by weight of cross-linked insoluble PVPP, and, if appropriate, one or more further pharmaceutical auxiliaries and excipients. These preparations show a good release of dihydropyridine with good content uniformity. * * * * *

414265

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