Solid, stabilized, prompt- and/or modified-release...

A - Human Necessities – 61 – K

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Details

A61K 9/48 (2006.01) A61K 9/16 (2006.01) A61K 47/10 (2006.01) A61K 47/14 (2006.01)

Patent

CA 2466529

A process for the formulation of liquid active ingredients in solid pharmaceutical, dietetic or alimentary compositions. The process comprises adding the active ingredients to a molten mass consisting of amphiphilic compounds with melting or softening point ranging from 30~C to 60~C and/or by lipophilic compounds with melting point ranging from 40~C to 90~C, and optionally adding powder active pharmaceuticals ingredients or excipients, then formulating the final compositions.

L'invention concerne un procédé de formulation d'ingrédients actifs liquides dans des compositions pharmaceutiques, diététiques ou alimentaires solides. Ce procédé consiste à ajouter les ingrédients actifs à une masse fondue faite de composés amphiphiles avec un point de fusion ou de ramollissement allant de 30 ·C à 60 ·C, et/ou de composés lipophiles avec un point de fusion allant de 40 ·C à 90 ·C, et éventuellement à ajouter des ingrédients ou des excipients pharmaceutiques actifs en poudre, puis à formuler les compositions finales.

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