C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 277/34 (2006.01) A61K 31/425 (2006.01)
Patent
CA 2391429
The present invention provides a crystal form, termed E type crystal form, and an amorphous form of 5-[[6-[(2-fluorophenyl)methoxy]-2-naphthalenyl]methyl]- 2,4-Thiazolidinedione (MCC-555) that are distinguishable from known crystal forms. The present invention also provides a method for preparation thereof and pharmaceutical compositions comprising the E type crystal form, or amorphous forms of MCC-555.
La présente invention concerne une forme cristalline, appelée forme cristalline du type E, et une forme amorphe de 5-[[6-[(2-fluorophényl)méthoxy]-2-naphtalényl]méthyl]-2,4-thiazolidinedione (MCC-555) qu'il est possible de distinguer des formes cristallines connues. La présente invention concerne également un procédé de préparation desdites formes, ainsi que des compositions pharmaceutiques renfermant la forme cristalline du type E ou des formes amorphes de MCC-555.
Andres Mark C.
Bryn Stephen R.
Newman Ann W.
Russell Catherine
Ogilvy Renault
Ortho-Mcneil Pharmaceutical Inc.
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