Solid state forms of aliskiren compounds

C - Chemistry – Metallurgy – 07 – C

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C07C 237/20 (2006.01) A61K 31/165 (2006.01)

Patent

CA 2724152

The invention relates to solid states of pharmaceutically acceptable compounds of aliskiren, and processes for preparation thereof. The invention further provides pharmaceutical formulations comprising the amorphous or crystal line forms of pharmaceutically acceptable compounds of aliskiren and processes thereof; and a method of inhibiting renin for treating hypertension.

L'invention concerne des formes à l'état solide de composés d'aliskirène pharmaceutiquement acceptables, et des procédés pour les préparer. L'invention concerne en outre des formulations pharmaceutiques comprenant les formes amorphes ou cristallines de composés d'aliskirène pharmaceutiquement acceptables et des procédés associés, et un procédé d'inhibition de la rénine pour traiter l'hypertension.

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