Solid states forms of varenicline salts and processes for...

C - Chemistry – Metallurgy – 07 – D

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C07D 471/18 (2006.01) A61K 31/4995 (2006.01) A61P 25/34 (2006.01)

Patent

CA 2708723

Salts and crystalline forms of several salts of Varenicline, i.e., Varenicline sulfate, Varenicline mesylate, and Varenicline fumarate, methods of preparing the solid states of Varenicline sulfate, Varenicline mesylate, and Varenicline fumarate, and processes for preparing Varenicline base from those Varenicline salts are provided.

Cette invention concerne des sels et des formes cristallines de plusieurs sels de Varénicline, à savoir, sulfate de Varénicline, mésylate de Varénicline, et fumarate de Varénicline, des procédés de préparation de formes solides de sulfate de Varénicline, mésylate de Varénicline, et fumarate de Varénicline, et des procédés de préparation d'une base Varénicline à partir desdits sels de Varénicline.

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