A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/35 (2006.01) A61K 9/00 (2006.01)
Patent
CA 2624503
The invention relates to a solid vaccine formulation adapted for mucosal administration comprising at least one antigen as active substance, wherein the formulation comprises a lyophilisate of a suspension comprising an oxygen- containing metal salt, the antigen(s) and one or more excipients selected from (i) saccharides, (ii) sugar alcohols, and (iii) amino acids or pharmaceutically acceptable salts thereof.
La présente invention concerne une formulation vaccinale solide convenant pour une administration par voie muqueuse, comprenant au moins un antigène comme substance active. Ladite formulation comprend un lyophilisat d~une suspension comprenant un sel métallique contenant de l~oxygène, l~antigène(s) ainsi qu~un ou des excipients sélectionnés à partir de (i) saccharides, (ii) polyols, ainsi que (iii) des acides aminés ou sels pharmaceutiquement acceptables de ceux-ci.
Hejl Charlotte
Ipsen Hans-Henrik
Lund Maerkedahl Lise
Lundegaard Annette Rommelmayer
Seppaelae Ulla
Alk-Abello A/s
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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