A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/435 (2006.01) C07D 453/02 (2006.01)
Patent
CA 2560080
A novel process for producing a composition containing either solifenacin or a salt thereof; and a composition containing either solifenacin or a salt thereof obtained by the production process, which contains a solifenacin compound having an optionally substituted lower alkyl bonded to the 2-position of the quinuclidine. The composition contains solifenacin in a high purity, and contains, only in an extremely small amount, unexpected compounds which are peculiar to the production process. It hence has extremely preferable properties required of ingredients for medicines.
Un nouveau processus en vue de produire une composition contenant soit de la solifenacine soit du sel ; une composition contenant soit de la solifenacine soit du sel ainsi obtenue par le processus de production et qui contient un composant de solifenacine comprenant de l~alkyle inférieur utilisé en remplacement, lié en position 2 du quinuclidine. La composition contient de la solifenacine de haute pureté ainsi que des composants inattendus, mais seulement en très petites quantités, spécifiques au processus de production. De ce fait, la composition possède des propriétés hautement supérieures nécessaires aux ingrédients utilisés pour les médicaments.
Inakoshi Masatoshi
Ishii Yusuke
Astellas Pharma Inc.
Dennison Associates
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