C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 453/02 (2006.01) A61K 31/439 (2006.01) A61P 1/12 (2006.01) A61P 13/02 (2006.01) A61P 27/08 (2006.01)
Patent
CA 2558877
A composition comprising solifenacin succinate with the content of impurities reduced, which can be used as a pharmaceutical primary material. This composition comprising solifenacin succinate is especially featured by reduction of the content of optical isomers thereof as compared with the conventional compositions containing solifenacin acid adduct salts and can be used in the production of pharmaceutical products containing solifenacin succinate. There is further provided a process for easily producing this composition comprising solifenacin succinate.
Composition comprenant du succinat de solifénacine dont la teneur en impureté a été réduite, qui peut être utilisée en tant que substance pharmaceutique primaire. Cette composition comprenant du succinate de solifénacine est caractérisée en particulier par la réduction de la teneur en isomères optiques par comparaison avec les compositions conventionnelles contenant des sels d'addition à un acide de solifénacine et peut être utilisée pour la production de produits pharmaceutiques contenant du succinate de solifénacine. Il est en outre proposé un procédé pour produire facilement cette composition comprenant du succinate de solifénacine.
Inakoshi Masatoshi
Ishii Yusuke
Nagata Koji
Nakagawa Shuichi
Takaoka Kouji
Astellas Pharma Inc.
Dennison Associates
LandOfFree
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