Solubilisation of drugs in hfa propellant by means of emulsions

A - Human Necessities – 61 – K

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

A61K 9/72 (2006.01) A61K 9/00 (2006.01) A61K 9/107 (2006.01)

Patent

CA 2488354

Emulsion and microemulsion aerosol formulations in a HFA propellant system include a medicament, one or more surfactant, optionally a cosolvent and water. Emulsion formulations are based on 0.1-% w/w surfactant and 1-10% w/w water. Microemulsion formulations are based on 1-20% w/w surfactant, 1-30% w/w cosolvent and 1-10% w/w water. Preferred surfactant are Span 85, AOT and their blends, synperonics and alkylpolyglucosides (APGs) The preferred cosolvent is ethanol.

L'invention concerne des formulations aérosol sous forme d'émulsion et de microémulsion dans un système propulseur HFA comprenant un médicament, un ou plusieurs tensioactif(s), éventuellement un cosolvant et de l'eau. Les formulations sous forme d'émulsion comprennent entre 0,1 et 2 % masse pour masse de tensioactif et entre 1 et 10 % masse pour masse d'eau. Les formulations sous forme de microémulsion comprennent entre 1 et 20 % masse pour masse de tensioactif, entre 1 et 30 % masse pour masse de cosolvant et entre 1 et 10 % masse pour masse d'eau. Les tensioactifs préférés sont le Span 85, l'AOT et leurs mélanges, un copolymère Synperonic et des alkyles polyglucosides (APG). Le cosolvant préféré est de l'éthanol.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Solubilisation of drugs in hfa propellant by means of emulsions does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Solubilisation of drugs in hfa propellant by means of emulsions, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Solubilisation of drugs in hfa propellant by means of emulsions will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1600997

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.