Solubilization of hydrophobic materials using lysophospholipids

Details Solubilization of hydrophobic materials using lysophospholipids Solubilization of hydrophobic materials using lysophospholipids

A - Human Necessities

61

K

167/163

A61K 31/685 (2006.01) A61K 9/127 (2006.01) A61K 47/24 (2006.01)

Patent

CA 1303990

TLC 122 SOLUBILIZATION OF HYDROPHOBIC MATERIALS USING LYSOPHOSPHOLIPID ABSTRACT A method and composition are described for the solubilization of hydrophobic materials using a lysophospholipid. The method includes drying a composition comprising a hydrophobic material-solubilizing effective amount of phospholipid from organic solvent and hydrating the resulting film with an aqueous medium at either a pH of between about 8.5 ant about 14.0, or at pH 7.0 followed by reduction of the temperature to less than 0°C.

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