Soluble cd40l(cd154) as a prognostic marker of...

G - Physics – 01 – N

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Details

G01N 33/92 (2006.01) A61K 38/17 (2006.01) A61K 45/00 (2006.01) G01N 33/53 (2006.01) G01N 33/543 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2464531

This invention involves the new use of a diagnostic test to determine the risk of atherosclerotic diseases such as myocardial infarction and stroke, particularly among individuals with no signs or symptoms of current disease and among nonsmokers. Further, this invention involves the new use of a diagnostic test to assist physicians in determining which individuals at risk will preferentially benefit from certain treatments designed either to prevent first or recurrent myocardial infarctions and strokes, or to treat acute and chronic cardiovascular disorders. Methods for treatment are also described.

L'invention concerne l'utilisation d'un test de diagnostic pour déterminer le risque de maladies artérioscléreuses telles que l'infarctus du myocarde ou l'accident cérébrovasculaire, notamment chez les personnes n'ayant ni signes ni symptômes de maladie en cours et chez les non-fumeurs. La présente invention porte également sur l'utilisation d'un test de diagnostic pour aider les médecins à déterminer quelles personnes à risque peuvent bénéficier de préférence de certains traitements conçus soit pour prévenir un premier infarctus du myocarde ou accident cérébrovasculaire ou des infarctus du myocarde ou des accidents cérébrovasculaires récurrents, ou bien pour traiter des troubles cardiovasculaires aigus et chroniques. La présente invention concerne aussi des méthodes thérapeutiques.

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