Soluble fragments of the sars-cov spike glycoprotein

A - Human Necessities – 61 – K

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Details

A61K 39/215 (2006.01) A61K 39/42 (2006.01) C07K 9/00 (2006.01) C07K 14/005 (2006.01) C12N 15/00 (2006.01) C12P 21/00 (2006.01)

Patent

CA 2637730

The invention relates to the spike protein from the virus (SARS-CoV) that is etiologically linked to severe acute respiratory syndrome (SARS); polypeptides and peptide fragments of the spike protein; nucleic acid segments and constructs that encode the spike protein, polypeptides and peptide fragments of the spike protein, and coupled proteins that include the spike protein or a portion thereof; peptidomimetics; vaccines; methods for vaccination and treatment of severe acute respiratory syndrome; antibodies; aptamers; and kits containing immunological compositions, or antibodies (or aptamers) that bind to the spike protein.

La présente invention concerne la protéine de spicule du virus (SRAS-CoV) qui est lié étiologiquement au syndrome respiratoire aigu sévère (SRAS) ; des fragments de polypeptides et peptides de la protéine de spicule ; des segments et des constructions d~acide nucléique qui codent pour la protéine de spicule, des fragments de polypeptides et peptides de la protéine de spicule ; et des protéines couplées qui incluent la protéine de spicule ou une partie de celle-ci ; des peptidomimétiques ; des vaccins ; des procédés de vaccination et un traitement du syndrome respiratoire aigu sévère ; des anticorps ; des aptamères ; et des kits contenant des compositions immunologiques, ou des anticorps (ou aptamères) qui se lient à la protéine de spicule.

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