C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/04 (2006.01) A61K 31/4427 (2006.01) A61K 31/4439 (2006.01) C07D 401/14 (2006.01) C07D 403/04 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01) C07D 417/04 (2006.01) C07D 417/14 (2006.01)
Patent
CA 2698332
A compound having the structure I useful for treatment or prevention of cardiovascular diseases, endothelial dysfunction, diastolic dysfunction, atherosclerosis, hypertension, angina pectoris, thromboses, restenoses, myocardial infarction, strokes, cardiac insufficiency, pulmonary hypertonia, erectile dysfunction, asthma bronchiale, chronic kidney insufficiency, diabetes, or cirrhosis of the liver in a human or animal patient.
L'invention se rapporte à un composé de structure I utile pour traiter ou prévenir les maladies cardiovasculaires, le dysfonctionnement endothélial, le dysfonctionnement diastolique, l'athérosclérose, l'hypertension, l'angor, les thromboses, les resténoses, l'infarctus du myocarde, les AVC, l'insuffisance cardiaque, l'hypertonie pulmonaire, les troubles de l'érection, l'asthme bronchique, l'insuffisance rénale chronique, le diabète ou la cirrhose hépatique chez un patient humain ou chez un animal.
Bittner Amy R.
Chang Jiang
Kim Ronald M.
Mirc J. W.
Parmee Emma R.
Merck Sharp & Dohme Corp.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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