C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/04 (2006.01) A61K 31/505 (2006.01) C07D 233/36 (2006.01) C07D 233/38 (2006.01)
Patent
CA 2089956
HOE 92/F 048 Abstract of the disclosure Soluble salts of 4-amino-2-(4,4-dimethylimidazolidin-2- on-1-yl)pyrimidine-5-carboxylic acid N-methyl-N-(3- trifluoromethylphenyl)amide, a process for the prepara- tion thereof, the use thereof as pharmaceuticals and starting materials Salts, which are soluble and freely soluble in water, of 4-amino-2-(4,4-dimethylimidazolidin-2-on-1-yl)pyrimidine- 5 carboxylic acid N-methyl-N-(3-trifluoromethylphenyl)- amide and a process for the preparation thereof are described. The compounds are suitable for the treatment of lipid metabolism disorders which are beneficially influenced by stimulation of the hepatic LDL receptor. Also described are the compounds of the formula IV Image IV and the salts thereof.
Granzer Ernold
Huttinger Manfred
Kampe Klaus-Dieter
Leineweber Michael
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Hoechst Aktiengesellschaft
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