Soluble tcr fusion molecules and methods of use

Details Soluble tcr fusion molecules and methods of use Soluble tcr fusion molecules and methods of use

G - Physics

01

N

G01N 33/574 (2006.01) C12Q 1/04 (2006.01) C40B 30/04 (2006.01) G01N 33/567 (2006.01)

Patent

CA 2544483

Disclosed are compositions and methods for detecting cells or tissue comprising a peptide antigen presented in the context of an MHC or HLA complex. The invention has a wide range of applications including providing a highly sensitive method for detecting cancer cells.

La présente invention concerne des compositions et des procédés pour détecter des cellules ou des tissus comprenant un antigène peptidique présenté dans le contexte d'un complexe MHC ou HLA. Cette invention présente une vaste gamme d'applications, notamment un procédé à haute sensibilité pour détecter des cellules cancéreuses.

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