Soluble tnf receptors and their use in treatment of disease

Details Soluble tnf receptors and their use in treatment of disease Soluble tnf receptors and their use in treatment of disease

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) C07H 21/00 (2006.01) C07K 14/715 (2006.01) C12N 15/11 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2666981

The present invention relates to tumor necrosis factor (TNF) antagonists and corresponding nucleic acids derived from tumor necrosis factor receptors (TNFRs) and their use in the treatment of inflammatory diseases. These proteins are soluble secreted decoy receptors that bind to TNF and prevent TNF from signaling to cells. In particular, the proteins are mammalian TNFRs that lack exon 7 and which can bind TNF and can act as a TNF antagonist.

La présente invention concerne des antagonistes du facteur onconécrosant (TNF) et les acides nucléiques correspondants dérivés des récepteurs du facteur onconécrosant (TNFR) et leur utilisation pour le traitement de maladies inflammatoires. Ces protéines sont des récepteurs leurres secrétés solubles qui se lient au TNS et empêchent le signalement du TNF aux cellules. Les protéines sont notamment des TNFR mammaliens auxquelles manque exon 7 et qui peuvent se lier au TNF et agir en tant qu'antagoniste du TNF.

Affiliated with

Also associated with

Rating

Soluble tnf receptors and their use in treatment of disease does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Soluble tnf receptors and their use in treatment of disease, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Soluble tnf receptors and their use in treatment of disease will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1591914