A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61P 11/00 (2006.01) A61P 17/00 (2006.01) A61P 25/00 (2006.01) A61P 37/00 (2006.01)
Patent
CA 2416250
The invention pertains to methods and compositions for treating medical disorders characterized by elevated levels or abnormal expression of TNF.alpha. by administering a TNF.alpha. inhibitor, such as recombinant TNFR:Fc, and to combination treatments involving the administration of a TNF.alpha. inhibitor and an IL-4 inhibitor. Also provided are methods and compositions involving IL-4 inhibitors for use in treating neurological disorders.
L'invention concerne des méthodes et des compositions de traitement d'affections médicales caractérisées par des niveaux élevés ou une expression anormale du TNF.alpha., grâce à l'administration d'un inhibiteur du TNF.alpha., par exemple un TNFR:Fc de recombinaison, et des traitements combinés consistant à administrer un inhibiteur du TNF.alpha. et un inhibiteur de l'IL-4. L'invention concerne également des méthodes et des compositions associées aux inhibiteurs de l'IL-4 utilisés dans le traitement des troubles neurologiques.
Connor Timothy
Pluenneke John D.
Immunex Corporation
Smart & Biggar
LandOfFree
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