C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 39/00 (2006.01) C07H 21/04 (2006.01) C07K 14/705 (2006.01) C07K 17/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/574 (2006.01) G01N 33/577 (2006.01) H01F 19/08 (2006.01)
Patent
CA 2120507
SOLUBLE VARIANTS OF TYPE I MEMBRANE PROTEINS, AND METHODS OF USING THEM ABSTRACT The present invention describes novel soluble variants of type I membrane protein GA733-2 and methods of making and using them. In addition, the present invention describes a method of converting type I membrane proteins into secretory proteins which may be used for active immunotherapy against carcinomas and as reagents in the detection of GA733-2 expression on tumor cells.
Herlyn Dorothee
Koprowski Hilary
Linnenbach Alban J.
Finlayson & Singlehurst
Wistar Institute Of Anatomy And Biology (the)
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