Solution structure of il-13 and uses thereof

Details Solution structure of il-13 and uses thereof Solution structure of il-13 and uses thereof

C - Chemistry, Metallurgy

07

K

C07K 14/54 (2006.01) G06F 17/50 (2006.01) G06F 19/00 (2006.01)

Patent

CA 2450147

The present invention relates to the three dimensional solution structure of interleukin-13 (IL-13), as well as the identification and characterization of various binding active sites of IL-13. Also provided for by the present invention are methods of utilizing the three dimensional structure for the design and selection of potent and selective agents that interact with IL-13.

L'invention concerne la structure de solution tridimensionnelle de l'interleukine-13 (IL-13), ainsi que l'identification et la caractérisation de différents sites actifs de liaison d'IL-13. L'invention concerne également des procédés pour utiliser cette structure tridimensionnelle pour la conception et la sélection d'agents sélectifs et puissants qui interagissent avec IL-13.

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