Solutions for the perfusion, preservation and reperfusion of...

A - Human Necessities – 61 – K

Patent

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A61K 38/06 (2006.01) A01N 1/02 (2006.01) A61K 31/195 (2006.01) A61K 33/14 (2006.01)

Patent

CA 2055827

Perfusion and preservation and/or reperfusion solutions for surgery and organ transplantation, including that of the heart, a feature of which solutions is the inclusion of at least one antioxidant compound, such as a trapping agent for free oxygen radicals, in particular glutathione in the reduced state or N-acetylcysteine, said solutions possessing a zero or greatly reduced partial pressure of oxygen which is maintained substantially at this value up to the time of use. The solution is preferably presented in flexible bags impermeable to oxygen.

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