Solutions of oxazaphosphorins having improved stability and...

Details Solutions of oxazaphosphorins having improved stability and... Solutions of oxazaphosphorins having improved stability and...

A - Human Necessities

61

K

167/250

A61K 31/675 (2006.01) A61K 47/00 (2006.01) A61K 47/10 (2006.01)

Patent

CA 1289886

ABSTRACT OF THE DISCLOSURE A solution of oxazaphosphorins of the general formula Image I wherein R1, R2 and R3 are the same or different and represent hydrogen, methyl, ethyl, 2-chloroethyl or 2-methanesulfonyloxy- ethyl and at least two of these radicals are 2-chloroethyl and/or 2-methanesulfonyloxyethyl, in 80-100% (v/v) ethanol, such that the oxazaphosphorin concentration is 10-70 percent (w/v) and a process for the preparation thereof.

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