Solutions viscoelastiques renfermant du hyaluronate de...

A - Human Necessities – 61 – L

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Details

A61L 31/04 (2006.01) A61K 9/00 (2006.01) A61K 47/36 (2006.01) A61L 24/04 (2006.01) A61L 24/08 (2006.01)

Patent

CA 2589397

The invention concerns aqueous biocompatible viscoelastic solutions based on a mixture of sodium hyaluronate(s) (NaHA) and hydroxypropylmethycellulose(s) (HPMC), containing more than 1 to 2 wt. % of at least one sodium hyaluronate whereof the average molecular weight ranges between 1.106 g/mol and 3,5.106 g/mol; and more than 0,2 to 1 wt. % of at least one hydroxypropylmethylcellulose whereof the average molecular weight ranges between 10 000 g/mol and 110 000 g/mol. The invention also concerns the preparation of said solutions and their use as accessories and/or temporary surgical implants in the form of hydrating implants.

La présente invention a pour objet : - des solutions aqueuses viscoélastiques biocompatibles à base d'un mélange de hyaluronate(s) de sodium (NaHA) et d'hydroxypropylméthylAEllulose(s) (HPMC), qui renferment ; + de 1 à 2 % en poids d'au moins un hyaluronate de sodium dont la masse moléculaire moyenne est comprise entre 1.106 g/ml et 3,5.106 g/mol ; et + de 0,2 à 1 % en poids d'au moins une hydroxypropylméthylcellulose dont la masse moléculaire moyenne est comprise entre 10 000 g/mol et 110 000 g/mol ; - la préparation desdites solutions ; et - leur utilisation à titre d'auxiliaires et/ou implants temporaires de chirurgie ainsi qu'à titre d'implants d'hydratation.

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