Solvates of b-lactam antibiotic

Details Solvates of b-lactam antibiotic Solvates of b-lactam antibiotic

C - Chemistry, Metallurgy

07

D

260/271

C07D 463/22 (2006.01) C07D 463/00 (2006.01)

Patent

CA 2002597

The crystalline bis(DMF), dihydrate mono(DMF) and mono(DMF) forms of 7.beta.-[2'-(R)-2'-phenyl-2'-amino-acetamido] -3-chloro-3-(1-carbadethiacephem)-4-carboxylic acid (LY163892) are useful intermediates to the monohydrate form of LY163892.

Les composés mono(DMF), mono(DMF) dihydraté et bis(DMF), sous forme cristalline, qui donnent de l'acide 7bêta-¢2'-(R)-2'-phényl-2'-amino-acétamido!-3-chloro-3-(1-carbadéthiacéphème)- 4-carboxylique (LY163892), sont utiles comme intermédiaires pour la forme monohydratée de LY163892.

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