Solvates of dirithromycin and a process for isolating form...

C - Chemistry – Metallurgy – 07 – H

Patent

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C07H 17/08 (2006.01) A61K 9/20 (2006.01) A61K 9/28 (2006.01)

Patent

CA 2067274

There is disclosed the acetone, 1-butanol, 1- propanol, and 2-propanol solvates of dirithromycin which provide an efficient means of isolating Form II dirithromycin. A process for isolating Form II dirithromycin from the solvates or from Form I dirithromycin is provided. A process for obtaining Form II dirithromycin from non-solvated dirithromycin is also provided.

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