Solvent-free anthracycline derivatives

Details Solvent-free anthracycline derivatives Solvent-free anthracycline derivatives

C - Chemistry, Metallurgy

07

H

C07H 15/252 (2006.01) A61K 31/704 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2453296

There are provided a method for making highly purified crystals of anthracycline derivatives, and a new crystalline form of 4-demethoxy-3'- deamino-3'-aziridinyl-4'-methansulfonyl daunorubicin, useful in the treatment of tumors.

L'invention concerne un procédé destiné à fabriquer des cristaux de dérivés d'anthracycline hautement purifiés, et une nouvelle forme cristalline de daunorubicine de 4-déméthoxy-3'-déamino-3'-aziridinyl-4'-méthansulfonyle, utilisée dans le traitement de tumeurs.

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