Somatostatin analogs and intermediates thereto

Details Somatostatin analogs and intermediates thereto Somatostatin analogs and intermediates thereto

C - Chemistry, Metallurgy

07

K

530/7.26

C07K 14/655 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1120030

Abstract of the Disclosure The tetradecapeptide D-Val-Gly-L-Cys-L-Lys-L- Asn-L-Phe-L-Phe-D-Trp-L-Lys-L-Thr-L-Phe-L-Thr-L-Ser-L-Cys-OH is described along with its corresponding non-toxic pharmaceutically-acceptable acid addition salts as well as intermediates useful in the synthesis of this tetradecapeptide. This tetradecapeptide is prepared by reacting the corresponding straight-chain tetradecapeptide with an oxidizing agent to con- vert the two sulfhydryl groups to a disulfide bridge. This tetradecapeptide as well as its pharmaceutically acceptable acid addition salts exhibit various activities including inhibition of the release of growth hormone and reduction of gut motility.

301485

Affiliated with

Also associated with

Rating

Somatostatin analogs and intermediates thereto does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Somatostatin analogs and intermediates thereto, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Somatostatin analogs and intermediates thereto will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-711831