Somatostatin antagonists and agonists that act at the sst...

Details Somatostatin antagonists and agonists that act at the sst... Somatostatin antagonists and agonists that act at the sst...

C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01) A61K 31/405 (2006.01) A61K 31/454 (2006.01) A61K 31/4545 (2006.01) A61K 31/495 (2006.01) A61K 31/496 (2006.01) A61K 31/5377 (2006.01) A61K 31/54 (2006.01) A61K 31/55 (2006.01) A61K 38/05 (2006.01) A61P 5/06 (2006.01) C07D 209/20 (2006.01) C07D 401/14 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 471/04 (2006.01) C07K 5/02 (2006.01) C07K 5/078 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2316767

Compounds according to the formula: Image and pharmaceutically acceptable salts, solvates or hydrates thereof; wherein group Ar is optionally substituted (C6-C10)aryl or (C1-C9)heteroaryl; X is a direct link, -CH2 -, -SO2 -, -CO-, -CHR1- where R1 is(C1-C6) alkyl, or -CR1'R" - where both R1' and R" are, independently, (C1-C6)alkyl; Y is N or CH; and Z and W are as herein defined, and pharmaceutical compositions thereof, and methods useful to facilitate secretion of growth hormone(GH) in mammals.

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