Somatostatin receptor radioligand with increased uptake

A - Human Necessities – 61 – K

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A61K 51/08 (2006.01)

Patent

CA 2341489

A radioligand comprising a peptide capable of binding to a receptor wherein the peptide is coupled to at least one chelating agent, which chelating agent is not coordinated to a metal ion under physiological conditions and a composition comprising said radioligand as a diagnostic or pharmaceutical and a kit for the detection of receptors.

L'invention concerne un radioligand comprenant un peptide capable de se lier à un récepteur, le peptide étant couplé à au moins un agent chélatant et cet agent chélatant n'étant pas coordonné à un ion métallique dans des conditions physiologiques. L'invention concerne également une composition comprenant ce radioligand comme agent diagnostique ou pharmaceutique, ainsi qu'une trousse de détection de récepteurs.

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