Somatotropin analogs

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

530/13, 195/1.22

C12N 15/18 (2006.01) A61K 38/27 (2006.01) C07K 14/61 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2005502

This invention provides mammalian somatotropin analogs, and in particular, bovine somatotropin analogs in which at least one of the cysteine amino acids at positions 53, 164, 181 or 189 has been replaced with serine. Also provided are methods for enhancing growth and lactation using such analogs.

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