Sorbents for removing toxicants from blood or plasma, and...

A - Human Necessities – 61 – L

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A61L 31/00 (2006.01) A61M 1/36 (2006.01) B01J 20/26 (2006.01) B01J 20/32 (2006.01) C02F 1/28 (2006.01)

Patent

CA 2217139

A sorbent for removing toxicants from blood or plasma includes a plurality of beads composed of hypercrosslinked polystyrene-type resin and having a surface which is modified so as to prevent adsorption of large proteins and platelets and to minimize activation of blood complement system without affecting noticeably accessibility of an inner adsorption space of the beads for small and middle-sized toxicant molecules.

Un sorbant pour enlever les substances toxiques dans le sang ou dans le plasma comprend une série de billes composées de résine de type polystyrène hyperréticulé et ayant une surface qui est modifiée de manière à empêcher l'absorption des grosses protéines et des plaquettes et à réduire l'activation du système complémentaire sanguin sans empêcher sensiblement les molécules de substances toxiques de petite et de moyenne taille d'accéder à un espace d'absorption interne des billes.

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