C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/31 (2006.01) C07H 21/04 (2006.01) C07K 14/00 (2006.01) C12P 19/34 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2331780
An M. paratuberculosis gene referred to as hspX provides a useful target region for the construction of suitable probes and primers that are species- specific for distinguishing M. paratuberculosis from related mycobacteria in a test sample. The Figure is a schematic diagram that shows a BamHI fragment containing the hspX open reading frame, as well as the position of an M. paratuberculosis species-specific probe (MP probe). M. paratuberculosis is the causative agent of Johne's disease and has been isolated from human patients with Crohn's disease.
L'invention concerne un gène M. paratuberculosis appelé hspX, constituant une cible utile pour l'élaboration de sondes et d'amorces appropriées qui permettent une identification spécifique au genre du M. paratuberculosis parmi les mycobactéries apparentées dans un échantillon d'essai. La figure donne une représentation schématique d'un fragment BamHI renfermant le cadre de lecture ouvert hspX, ainsi que la position d'une sonde spécifique au genre du M. paratuberculosis. Le M. paratuberculosis, qui est à l'origine de la maladie de Johne (paratuberculose), a été isolé chez des patients atteints de la maladie de Crohn.
Ellingson Jay L. E.
Stabel Judith R.
Borden Ladner Gervais Llp
The United States Of America As Represented By The Secretary Of Agricul Ture
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