Specific analysis of ketone and aldehyde analytes using...

G - Physics – 01 – N

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G01N 37/00 (2006.01)

Patent

CA 2762277

Labeling reagents, sets of labeling reagents, and labeling techniques are provided for the relative quantitation, absolute quantitation, or both, of ketone or aldehyde compounds including, but not limited to, analytes comprising steroids or ketosteroids. The analytes can be medical or pharmaceutical compounds in biological samples. Methods for labeling, analyzing, and quantifying ketone or aldehyde compounds are also disclosed as are methods that also use mass spectrometry.

L'invention porte sur des réactifs de marquage, sur des ensembles de réactif de marquage et sur des techniques de marquage pour la quantification relative, la quantification absolue, ou les deux, de composés de cétone ou d'aldéhyde comprenant, mais sans y être limités, des analytes comprenant des stéroïdes ou des cétostéroïdes. Les analytes peuvent être des composés médicaux ou pharmaceutiques dans des échantillons biologiques. L'invention porte également sur des procédés pour le marquage, l'analyse et la quantification de composés de cétone ou d'aldéhyde, ainsi que sur des procédés qui utilisent également une spectrométrie de masse.

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