Specific antibodies for use in preparation of pharmaceutical...

C - Chemistry – Metallurgy – 07 – K

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Details

C07K 16/40 (2006.01) A23L 1/03 (2006.01) A61K 39/40 (2006.01) C07K 16/02 (2006.01) C07K 16/12 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2234565

The present invention provides specific antibodies obtained from eggs laid by hens which have been immunized against urease of Helicobacter pylori as an antigen, and specific antibodies obtained from eggs laid by hens which have been immunized against flagella of Helicobacter pylori as an antigen. These antibodies are useful for the prevention or treatment of gastritis, gastric ulcers and duodenal ulcers caused by infection of Helicobacter pylori. At least one organism selected from lactic acid bacteria, Enterococcuses, yeasts, and Baillus can be used along with the antibodies.

La présente invention concerne des anticorps spécifiques obtenus à partir d'oeufs pondus par des poules ayant été immunisées contre l'uréase de Helicobacter pylori en tant qu'antigène, et des anticorps spécifiques obtenus à partir d'oeufs pondus par des poules ayant été immunisées contre la flagelle de Helicobacter pylori en tant qu'antigène. Ces anticorps sont utiles pour la prévention ou le traitement de la gastrite, de l'ulcère gastrique et de l'ulcère duodénal causées par une infection par Helicobacter pylori. Au moins un organisme choisi parmi les bactéries d'acide lactique, les entérocoques, les levures et le Baillus peut être utilisé conjointement avec les anticorps.

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