Specific binding agents

Details Specific binding agents Specific binding agents

C - Chemistry, Metallurgy

12

N

C12N 15/62 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61K 49/00 (2006.01) C07K 16/40 (2006.01) C07K 16/46 (2006.01) C12N 1/21 (2006.01) C12N 15/13 (2006.01) C12N 15/70 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2066670

2066670 9107500 PCTABS00005 A reshaped human antibody or reshaped human antibody fragment having specificity for human placental alkaline phosphatase (PLAP) is produced by transferring the complementarity determining regions (CDRs) from a murine anti-PLAP hybridoma cell line H17E2 into a human antibody variable region framework. The reshaped molecule can be used in the treatment or diagnosis of cancer.

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