Specific inhibition of allorejection

Details Specific inhibition of allorejection Specific inhibition of allorejection

A - Human Necessities

61

K

A61K 48/00 (2006.01) A01N 1/00 (2006.01) A61K 35/12 (2006.01) A61K 38/17 (2006.01) A61P 37/06 (2006.01) C07K 14/705 (2006.01) C12N 5/10 (2006.01) C12N 15/12 (2006.01) C12N 15/85 (2006.01)

Patent

CA 2522380

The present invention provides methods and compositions for specifically inhibiting both cellular and humoral immune responses to alloantigen, thereby finding use in extending the survival of transplant allografts and treating graft versus host disease in transplant recipients.

La présente invention se rapporte à des méthodes et à des compositions permettant d'inhiber de manière spécifique les réponses immunitaires à la fois cellulaires et humorales à un alloantigène, et qui sont par conséquent utiles pour allonger la durée de survie d'allogreffons et pour traiter la réaction du greffon contre l'hôte chez les receveurs desdits greffons.

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