A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 48/00 (2006.01) C07K 19/00 (2006.01) C12N 15/62 (2006.01) C12N 15/63 (2006.01)
Patent
CA 2574802
The present invention provides compositions and methods for specifically inhibiting host immune responses against autoantigens. In particular, compositions and methods combining CD8 polypeptide expression with autoantigen expression or presentation are described for specifically inhibiting the humoral and cellular components of the host immune response to autoantigens.
Présente invention concerne des compositions et des techniques permettant d'inhiber spécifiquement des réponses immunes d'hôte contre des auto-antigènes. Cette invention concerne en particulier des compositions et des techniques combinant l'expression de polypeptides CD8 avec l'expression d'auto-antigènes ou des présentations permettant d'inhiber spécifiquement des composants humoraux et cellulaires de la réponse immune d'hôte à des auto-antigènes
Qi Yan
Staerz Uwe D.
Isogenis Inc.
Smart & Biggar
LandOfFree
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