Specific n-terminal labeling of peptides and proteins in...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/25 (2006.01) C12P 21/00 (2006.01) C12Q 1/37 (2006.01) G01N 33/58 (2006.01) G01N 33/68 (2006.01) C07K 1/13 (2006.01) C07K 7/06 (2006.01)

Patent

CA 2675776

This invention provides general methods for selective labeling of proteins on their N-termini with synthetic peptides. The methods of this invention can be applied to the global proteomic profiling of complex mixtures of proteins and polypeptides.

L'invention concerne des procédés généraux pour le marquage sélectif de protéines sur leur extrémité N avec des peptides synthétiques. Les procédés de la présente invention peuvent être appliqués au profilage protéomique global de mélanges complexes de protéines et de polypeptides.

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