Specific peptide bond cleavage by organic tertiary...

C - Chemistry – Metallurgy – 07 – F

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C07F 9/50 (2006.01) C07F 9/547 (2006.01) C07F 9/572 (2006.01) C07F 9/6506 (2006.01) C07K 1/12 (2006.01) G01N 33/68 (2006.01)

Patent

CA 1330800

SPECIFIC PEPTIDE BOND CLEAVAGE BY NUCLEOPHILIC TERTIARY ORGANOPHOSPHINES ABSTRACT OF DISCLOSURE Novel nucleophilic tertiary organophosphines and the specific cleavage of peptide bonds by nucleophilic tertiary organophosphines. This invention is of particular utility in providing chemical agents for use in the cleavage of proteins and the determination o the amino acid sequence of protein.

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