Sperm factor oscillogenin

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/00 (2006.01) A23J 1/00 (2006.01) C07H 21/04 (2006.01) C07K 14/47 (2006.01) C07K 16/00 (2006.01) C12P 21/06 (2006.01) C12Q 1/00 (2006.01) A61K 35/12 (2006.01) A61K 38/00 (2006.01) C12N 5/06 (2006.01)

Patent

CA 2402722

The specification describes a novel compound, oscillogenin, which is an active agent in furthering oocyte fertilization by sperm or in parthenogenetic activation of an oocyte. The specification discloses methods of isolating oscillogenin to modulate fertility and to enhance parthenogenetic activation of oocytes for nuclear transfer or in ICSI procedures, and methods of using oscillogenin to test amounts of it in sperm and thus sperm fertility.

L'invention concerne un composé, l'oscillogénine, qui est un agent actif améliorant la fertilisation d'oocyte par un sperme ou l'activation parthénogénétique d'un oocyte. Elle concerne aussi des procédés d'extraction de l'oscillogénine dans le but de moduler la fertilité ou d'augmenter l'activation parthénogénétique d'oocytes aux fins de transfert nucléaire ou de procédures d'injection intracytoplasmique de sperme (ICSI), ainsi que des méthodes d'utilisation d'oscillogénine afin de tester en quelle quantité elle est présente dans le sperme et de tester ainsi la fertilité du sperme.

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