Sperm protective polypeptides and uses thereof

Details Sperm protective polypeptides and uses thereof Sperm protective polypeptides and uses thereof

C - Chemistry, Metallurgy

07

K

C07K 14/47 (2006.01) A01N 1/02 (2006.01) A61K 35/52 (2006.01) A61K 38/17 (2006.01)

Patent

CA 2542479

The present invention relates to polypeptides capable of binding chaperone receptors, composition and methods for protecting, restoring, or improving the physiological properties of sperm cells. More particularly, the invention relates to protection of the motility, survival, fertility capability, resistance to cooling, freezing, and thawing of sperm cells put in contact with chaperone polypeptides.

La présente invention concerne des polypeptides capables de se lier à des récepteurs de chaperon moléculaire, une composition et des méthodes de protection, de restauration ou d'amélioration des propriétés physiologiques de spermatozoïdes. Plus spécifiquement, ladite invention a pour objet la protection de la mobilité, de la survie, de la capacité de fertilité, de la résistance au refroidissement, à la congélation et à la décongélation de spermatozoïdes mis en contact avec des polypeptides de chaperon moléculaire.

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