Sperm specific antigens 4.1 and 6.7, dna encoding them and...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 39/00 (2006.01) C07K 14/00 (2006.01) C07K 14/47 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2296002

The present invention is directed to mammalian sperm specific proteins 4.1 and 6.7, and nucleotide sequences encoding said proteins, as well as pharmaceutical formulations, in particular vaccines comprising said proteins. The proteins 4.1 and 6.7 are sperm specific and can be used in a vaccine to prevent or reduce fertility in subjects.

Cette invention concerne des protéines 4,1 et 6,7 spécifiques du sperme de mammifères, les séquences nucléotidiques codant ces protéines ainsi que des formulations pharmaceutiques, plus particulièrement des vaccins contenant lesdites protéines. Les protéines 4,1 et 6,7 sont spécifiques du sperme et peuvent être utilisées dans un vaccin pour bloquer ou réduire la fertilité chez l'homme.

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