A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/135 (2006.01) A61K 38/20 (2006.01) A61K 38/21 (2006.01) A61K 45/06 (2006.01) A61P 25/00 (2006.01)
Patent
CA 2499622
Disclosed are pharmaceutical combinations comprising at least one S1P receptor agonist, as well as a method for treating demyelinating diseases, e.g. multiple sclerosis or disorders associated therewith or Guillain-Barré syndrome, comprising co-administration, e.g. concomitantly or in sequence, of a therapeutically effective amount of a) an S1P receptor agonist, and b) at least one co-agent shown to have clinical activity against at least one symptom of a demyelinating disease.
L'invention concerne des combinaisons pharmaceutiques contenant au moins un agoniste du récepteur de S1P, ainsi qu'un procédé de traitement de maladies de démyélinisation, par exemple de la sclérose en plaques, ou de troubles associés au syndrome de Guillain-Barré. Le procédé selon l'invention consiste à co-administrer, de façon simultanée ou séquencée, une quantité thérapeutique efficace a) d'un agoniste du récepteur de S1P, et b) d'au moins un co-agent présentant une activité clinique contre au moins un symptôme d'une maladie de démyélinisation.
Foster Carolyn Ann
Glue Paul William
Hiestand Peter C.
Fetherstonhaugh & Co.
Novartis Ag
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