Sphingosine kinase and uses thereof

Details Sphingosine kinase and uses thereof Sphingosine kinase and uses thereof

C - Chemistry, Metallurgy

12

N

C12N 15/54 (2006.01) A61K 31/13 (2006.01) A61K 35/14 (2006.01) A61K 38/00 (2006.01) C12N 9/12 (2006.01)

Patent

CA 2408196

The present invention relates generally to a method of modulating the growth of cells and, more particularly, to a method of down-regulating the growth of neoplastic cells. The present invention is useful, inter alia, in the therapeutic and/or prophylactic treatment of cancers such as, but not limited to, solid cancers such as cancers of the colon, stomach, lung, brain, bone, oesophagus, pancreas, breast, ovary or uterus.

La présente invention concerne, de manière générale, un procédé de modulation de la croissance des cellules, et en particulier, un procédé de diminution du nombre de cellules néoplasiques. La présente invention est utilisée, entre autres, dans le cadre du traitement thérapeutique et/ou prophylactique des cancers, notamment, mais pas exclusivement, les cancers solides tels que les cancers du colon, de l'estomac, du poumon, du cerveau, des os, de l'oesophage, du pancréas, du sein, de l'ovaire ou de l'utérus.

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