Sphingosine kinase, cloning, expression and methods of use

Details Sphingosine kinase, cloning, expression and methods of use Sphingosine kinase, cloning, expression and methods of use

C - Chemistry, Metallurgy

12

N

C12N 15/54 (2006.01) A61K 38/45 (2006.01) A61P 35/00 (2006.01) C07K 16/40 (2006.01) C12N 5/10 (2006.01) C12N 9/12 (2006.01) C12Q 1/48 (2006.01) C12Q 1/68 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2329124

The present invention relates to nucleic acids encoding sphingosine kinase (SPHK) and methods for use in producing sphingosine-1-phosphate (SPP), screening for inhibitors of SPHK, and as a therapeutic agent.

L'invention concerne des acides nucléiques codant la sphingosine kinase (SPHK), ainsi que des procédés d'utilisation de celle-ci dans la production de sphingosine-1-phosphate (SPP), dans le criblage des inhibiteurs de SPHK et en tant qu'agent thérapeutique.

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