Sphingosine kinase inhibitor prodrugs

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 233/60 (2006.01) A61K 31/165 (2006.01) A61K 31/222 (2006.01)

Patent

CA 2754601

The invention relates to prodrugs of hydroxyl-substituted adamantane compounds, pharmaceutical compositions thereof, and methods for inhibiting sphingosine kinase and for treating or preventing hyperproliferative disease, inflammatory disease, or angiogenic disease

Cette invention concerne des pro-médicaments de composés à base d'adamantane hydroxyl-substitué, leurs compositions pharmaceutiques, et des méthodes d'inhibition de la sphingosine kinase, de traitement et de prévention des maladies hyperprolifératives, des maladies inflammatoires ou des maladies angiogéniques.

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