Sphingosine kinase inhibitors

Details Sphingosine kinase inhibitors Sphingosine kinase inhibitors

C - Chemistry, Metallurgy

07

C

C07C 233/57 (2006.01) A61K 31/12 (2006.01) A61K 31/13 (2006.01) A61K 31/16 (2006.01) A61K 31/19 (2006.01) A61K 31/33 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) C07C 49/563 (2006.01) C07C 61/39 (2006.01) C07C 211/01 (2006.01) C07D 209/82 (2006.01) C07D 211/58 (2006.01) C07D 295/12 (2006.01)

Patent

CA 2612338

The invention relates to substituted adamantane compounds of formula (I), pharmaceutical compositions thereof, processes for their preparation, and methods for inhibiting sphingosine kinase and for treating or preventing hyperproliferative disease, imflammatory disease, or angiogenic disease.

L'invention concerne des composés d'adamantane substitués, des compositions pharmaceutiques renfermant ces composés, des procédés de préparation de ceux-ci et des procédés visant à inhiber la sphingosine kinase et à traiter ou à prévenir une maladie hyperproliférative, une maladie inflammatoire ou une maladie angiogénique.

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