Sphingosine kinase inhibitors and methods of their use

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 277/48 (2006.01) A61K 31/167 (2006.01) A61K 31/40 (2006.01) A61K 31/423 (2006.01) A61K 31/426 (2006.01) A61K 31/427 (2006.01) A61K 31/428 (2006.01) A61K 31/4409 (2006.01) A61K 31/4439 (2006.01) A61K 31/4465 (2006.01) A61K 31/496 (2006.01) A61K 31/5377 (2006.01) C07D 277/42 (2006.01) C07D 277/46 (2006.01) C07D 277/56 (2006.01)

Patent

CA 2617788

The invention relates to compounds, pharmaceutical compositions thereof, and methods for inhibiting sphingosine kinase and for treating or preventing hyperproliferative disease, inflammatory disease, or angiogenic disease.

L'invention concerne des composés, des compositions pharmaceutiques contenant ces composés, ainsi que des méthodes destinées à l'inhibition de la sphingosine kinase et au traitement ou à la prévention de maladies hyperprolifératives, inflammatoires ou angiogéniques.

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