C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 491/107 (2006.01) A61K 31/445 (2006.01) A61P 25/00 (2006.01) C07D 491/10 (2006.01)
Patent
CA 2389491
The present invention relates to spiro[2H-1-benzopyran-2,4'-piperidine] derivatives having general formula (I), wherein the substituents R1, R2, X and Y are ase defined in the claims or a pharmaceutically acceptable salt thereof. The invention also relates to pharmaceutical compositions comprising said derivatives, as well as to the use of these spiro[2H-1-benzopyran-2,4'-piperidine] derivatives in therapy, more specifically for the treatment of CNS disorders.
La présente invention concerne des dérivés de spiro[2H-1-benzopyran-2,4'-pipéridine], de formule générale (I), dans laquelle les substituants R¿1?, R¿2?, X et Y tels que définis dans les revendications ou un sel de ces dérivés, acceptable d'un point de vue pharmaceutique. La présente invention concerne également des compositions comprenant lesdits dérivés, ainsi que l'utilisation de ces dérivés de spiro[2H-1-benzopyran-2,4'-pipéridine] dans le domaine thérapeutique, plus spécialement pour le traitement de troubles du système nerveux central.
Gibson Samuel George
Miller David John
Akzo Nobel N.v.
Fetherstonhaugh & Co.
N.v. Organon
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