Spiro (4.5) decane derivatives, method for preparing them...

C - Chemistry – Metallurgy – 07 – D

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C07D 498/10 (2006.01) A61K 31/445 (2006.01) C07D 471/10 (2006.01) C07D 513/10 (2006.01)

Patent

CA 2050730

ABREGE NOUVEAUX DERIVES DU SPIRO[4.5]DECANE, LEUR PROCEDE DE PREPARATION ET LES COMPOSITIONS PHARMACEUTIQUES LES RENFERMANT. Nouveaux dérivés du spiro[4.5]décane, utilisables comme médicament et répondant à la formule : Image (I) dans laquelle X, A, Y, T, Z, R1, R2, R3, R4, R5 et R6 sont tels que définis dans la description. Ces dérivés et leurs sels physiologiquement tolérables peuvent être utilisés en thérapeutique notamment dans le traitement des dyslipidémies, de l'athérosclérose et des pathologies dans lesquelles une peroxydation lipidique membranaire joue un rôle initiateur et/ou aggravant.

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