Spiro-azabicyclic compounds useful in therapy

C - Chemistry – Metallurgy – 07 – D

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C07D 498/20 (2006.01) A61K 31/439 (2006.01) A61P 25/18 (2006.01) A61P 25/22 (2006.01) A61P 25/28 (2006.01) C07D 453/02 (2006.01) C07D 471/08 (2006.01)

Patent

CA 2196995

There are provided new compounds of formula (1), wherein R represents hydrogen or methyl; and n represents 1 or 2; or a pharmaceutically acceptable acid addition salt thereof, together with processes for preparing them, compositions containing them and their use in therapy. Compounds of formula (I) are expected to be useful in the treatment of psychotic disorders, intellectual impairment disorders and anxiety.

Nouveaux composés de formule (I) dans laquelle R représente hydrogène ou méthyle et n vaut 1 ou 2, ou sel d'addition d'acide pharmaceutiquement acceptable, ainsi que procédés de préparation desdits composés, compositions les contenant et leur utilisation en thérapie. Les composés de formule (I) sont utiles dans le traitement des troubles psychotiques, des troubles des facultés intellectuelles et de l'anxiété.

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